The Catawba River is a major river located in the Southeastern United States. It originates in Western North Carolina and flows into South Carolina, where it later becomes known as the Wateree River. The river is approximately 220 miles long. It rises in the Appalachian Mountains and drains into the Piedmont, where it has been impounded through a ser…The Catawba River is a major river located in the Southeastern United States. It originates in Western North Carolina and flows into South Carolina, where it later becomes known as the Wateree River. The river is approximately 220 miles long. It rises in the Appalachian Mountains and drains into the Piedmont, where it has been impounded through a series of reservoirs for flood control and generation of hydroelectricity. The river is named after the Catawba tribe of Native Americans, which lives on its banks. In their language, they call themselves "yeh is-WAH h’reh", meaning "people of the river."